Diethylamine → Benzoic Acid

HRID 375897

Reaktionsgleichung

Reaktionsgleichung von HRID 375897
Cl[C:2]1[CH:10]=[CH:9][C:8](S(F)(=O)=O)=[CH:7][C:3]=1[C:4]([OH:6])=[O:5].C(NCC)C>ClCCCl>[C:4]([OH:6])(=[O:5])[C:3]1[CH:7]=[CH:8][CH:9]=[CH:10][CH:2]=1

Komponenten

4

Edukt 2

HCID 8021DiethylamineHCID 888732-Chloro-5-(fluorosulpho)benzoic acid

Produkt 1

HCID 243Benzoic Acid

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 111,2-DichloroethaneLösungsmittel

Versuchsvorschrift

A mixture of 2-chloro-5-(fluorosulfonyl)benzoic acid (11.93 g, 0.05 mol), diethylamine (10.97 g, 0.15 mol) and 1,2-dichloroethane (100 mL) was refluxed for 8 hours. The reaction mixture was evaporated and the residue was dissolved in ethyl acetate. A solid was collected by filtration and the filtrate was evaporated to dryness to afford 15.5 g of 2-chloro-5-diethylaminosulfonyl)benzoic acid.

Aufarbeitung

  1. temperaturewas refluxed for 8 hours
  2. customThe reaction mixture was evaporated
  3. dissolutionthe residue was dissolved in ethyl acetate
  4. filtrationA solid was collected by filtration
  5. customthe filtrate was evaporated to dryness

Quellen und Nachweise

ORD-Eintrag
ord-498b6d423ed8427fba6d206335405625
Quelldatensatz
uspto-grants-1996_01
Patentnummer
US05488055

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