Acetone → 4-(4-Methylphenyl)-3-buten-2-one

HRID 38665

Reaktionsgleichung

Reaktionsgleichung von HRID 38665
O.[OH-].[Na+].[CH3:4][C:5]1[CH:12]=[CH:11][C:8]([CH:9]=O)=[CH:7][CH:6]=1.Cl.[CH3:14][C:15]([CH3:17])=[O:16]>>[CH3:4][C:5]1[CH:12]=[CH:11][C:8]([CH:9]=[CH:14][C:15](=[O:16])[CH3:17])=[CH:7][CH:6]=1

Komponenten

6

Edukt 5

HCID 180AcetoneHCID 313Hydrochloric AcidHCID 962WaterHCID 77254-MethylbenzaldehydeHCID 14798Sodium Hydroxide

Produkt 1

HCID 1073884-(4-Methylphenyl)-3-buten-2-oneAusbeute 45,6 %

Versuchsvorschrift

Water (20 ml) and 10% NaOH aqueous solution (4 ml) were added under stirring to the solution of 4-methylbenzaldehyde (10.2 g, 10 mmol) in acetone (10 ml). The reaction mixture was stirred for 14 hr at room temperature, then the pH value was adjusted to pH=7.0 with 10% hydrochloric acid, extracted with methylene chloride. The combined methylene chloride extract was washed with water, dried over anhydrous sodium sulfate, filtered and concentrated to give 0.73 g of a yellow viscous oil, yield: 45.6%.

Aufarbeitung

  1. extractionextracted with methylene chloride
  2. extractionThe combined methylene chloride extract
  3. washwas washed with water
  4. dry with materialdried over anhydrous sodium sulfate
  5. filtrationfiltered
  6. concentrationconcentrated

Quellen und Nachweise

ORD-Eintrag
ord-454981ae6c944075b3f892a7abf49cbe
Quelldatensatz
uspto-grants-2013_09
Patentnummer
US08524744B2

Verknüpfte Notizen

Wird geladen…