Hydrogen Peroxide → 3-Fluoroisonicotinic acid 1-oxide
Reaktionsgleichung
[F:1][C:2]1[CH:10]=[N:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=[O:5].[OH:11]O>C(O)(=O)C>[F:1][C:2]1[CH:10]=[N+:9]([O-:11])[CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=[O:5]Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Reaktionsbedingungen
- Temperatur
- 75 °C
Versuchsvorschrift
To a solution of 3-fluoroisonicotinic acid (5.0 g, 35.33 mmol) in acetic acid (25 ml) was added hydrogen peroxide (6 ml). The reaction mixture was stirred at 70-80° C. overnight. The solvent was removed to obtain 5.5 g of 3-fluoroisonicotinic acid 1-oxide in quantitative yield.
Aufarbeitung
- customThe solvent was removed
Quellen und Nachweise
- ORD-Eintrag
- ord-eefb4f777a6c4d60abf2477d1e1f9e78
- Quelldatensatz
- uspto-grants-2013_09
- Patentnummer
- US08524911B2
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