Water → HCID 178497263, Verbindung

HRID 400485

Reaktionsgleichung

Reaktionsgleichung von HRID 400485
C(O)(=O)C.[NH2:5][NH2:6].[CH3:7][O:8][C:9](=[O:21])[C:10](=O)[CH2:11][C:12](=O)[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1.O>C(O)(=O)C>[CH3:7][O:8][C:9]([C:10]1[CH:11]=[C:12]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[NH:6][N:5]=1)=[O:21]

Komponenten

5

Edukt 3

HCID 962WaterHCID 165591Hydrazine, acetate (1:1)HCID 308117Methyl 2,4-dioxo-4-phenylbutanoate

Produkt 1

HCID 178497263HCID 178497263, VerbindungAusbeute 66,3 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 176Acetic AcidLösungsmittel

Versuchsvorschrift

983 mg hydrazine acetate was added to 2 g 2,4-Dioxo-4-phenyl-butyric acid methyl ester in 10 mL concentrated acetic acid. The mixture was stirred over night at RT. Then water was added. The precipitate was filtered, stirred with diisopropylether and again filtered to give 1.3 g desired product. Rt: 1.39 min (method O), (M+H)+: 203

Aufarbeitung

  1. filtrationThe precipitate was filtered
  2. stirringstirred with diisopropylether
  3. filtrationagain filtered

Quellen und Nachweise

ORD-Eintrag
ord-8ffbecc03032464c90cc429146c8e351
Quelldatensatz
uspto-grants-2014_06
Patentnummer
US08741892B2

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