Water → 1,1'-(1-Bromoethane-1,2-diyl)dibenzene

To a solution of 12.0 (60.5 mmol) of 1,2-diphenylethanol in 50 mL of dry diethyl ether, 11.0 g (3.80 mL, 40.0 mmol) of PBr3 was added with vigorous stirring at −10° C. The resulting mixture was stirred for 12 hr at room temperature and then added to 350 mL of cold water. The organic layer was separated, and the aqueous layer was extracted with 2×100 mL of water. The combined organic extracts were washed with aqueous NaHCO3, dried over Na2SO4, and evaporated to dryness. This procedure gave 13.2 g (84%) of the title product.

1. stirringThe resulting mixture was stirred for 12 hr at room temperature
2. customThe organic layer was separated
3. extractionthe aqueous layer was extracted with 2×100 mL of water
4. washThe combined organic extracts were washed with aqueous NaHCO3
5. dry with materialdried over Na2SO4
6. customevaporated to dryness

ORD-Eintrag

ord-955a6e2a0d374c7495f12d087392dfcb

Quelldatensatz

uspto-grants-2013_09

DOI

10.6084/m9.figshare.5104873.v1

Patentnummer

US08530593B2