3-(2-Nitrophenyl)acrylic acid → Hydrocarbostyril

HRID 414551

Reaktionsgleichung

Reaktionsgleichung von HRID 414551
[N+:1]([C:4]1[CH:14]=[CH:13][CH:12]=[CH:11][C:5]=1[CH:6]=[CH:7][C:8](O)=[O:9])([O-])=O>C(O)C.[Pd]>[NH:1]1[C:4]2[C:5](=[CH:11][CH:12]=[CH:13][CH:14]=2)[CH2:6][CH2:7][C:8]1=[O:9]

Komponenten

4

Edukt 1

HCID 928203-(2-Nitrophenyl)acrylic acid

Produkt 1

HCID 64796Hydrocarbostyril

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

A solution of 25 g of o-nitrocinnamic acid in 250 ml of ethanol was shaken with 2.5 g of 10% palladium on carbon under hydrogen at a pressure of 3 atmospheres. When the theoretical amount of hydrogen had been absorbed the catalyst was filtered off, washed with hot ethanol and the filtrate evaporated under reduced pressure to give 3,4-dihydrocarbosytril, m.p. 168°-169° C.

Aufarbeitung

  1. customWhen the theoretical amount of hydrogen had been absorbed the catalyst
  2. filtrationwas filtered off
  3. washwashed with hot ethanol
  4. customthe filtrate evaporated under reduced pressure
  5. customto give 3,4-dihydrocarbosytril

Quellen und Nachweise

ORD-Eintrag
ord-5ddb15b8e8ef4e80b242fcfb9689bd83
Quelldatensatz
uspto-grants-1988_12
Patentnummer
US04792561

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