Reaktionsgleichung
[C:1]([O:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][O:12][C:13]1[CH:21]=[CH:20][C:16]([C:17]([OH:19])=[O:18])=[CH:15][CH:14]=1)(=[O:4])[CH:2]=[CH2:3].O[C:23]1[CH:36]=[CH:35][C:34]([OH:37])=[CH:33][C:24]=1[C:25]([O:27][CH2:28][C@@H:29]([CH3:32])[CH2:30][CH3:31])=[O:26].[CH2:38](Cl)[CH2:39]Cl>CN(C1C=CN=CC=1)C.C(Cl)Cl>[C:1]([O:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][O:12][C:13]1[CH:14]=[CH:15][C:16]([C:17]([O:19][C:23]2[CH:36]=[CH:35][C:34]([O:37][C:17](=[O:18])[C:16]3[CH:15]=[CH:14][C:13]([O:12][CH2:11][CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][O:5][C:1](=[O:4])[CH:38]=[CH2:39])=[CH:21][CH:20]=3)=[CH:33][C:24]=2[C:25]([O:27][CH2:28][C@@H:29]([CH3:32])[CH2:30][CH3:31])=[O:26])=[O:18])=[CH:20][CH:21]=1)(=[O:4])[CH:2]=[CH2:3]Komponenten
6
Edukt 3
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 2
Versuchsvorschrift
A mixture consisting of 4-{[6-(acryloyloxy)hexyl]oxy}benzoic acid (2.92 g), (2S)-2-methylbutyl 2,5-dihydroxybenzoate (1.1 g), DMAP (0.24 g) and EDC (2 g) in CH2Cl2 (30 ml) was stirred for 6 h at room temperature. The yellowish reaction mixture was then evaporated to dryness and the obtained pasty residue was purified by column chromatography over silica to give nearly pure material as transparent oil which becomes pasty upon standing for about 24 h.
Aufarbeitung
- customThe yellowish reaction mixture
- customwas then evaporated to dryness
- customthe obtained pasty residue was purified by column chromatography over silica
- customto give nearly pure material as transparent oil which
- waitupon standing for about 24 h.
Quellen und Nachweise
- ORD-Eintrag
- ord-14bc3a45110c4d50afb991f214510206
- Quelldatensatz
- uspto-grants-2012_01
- Patentnummer
- US08105662B2
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