Morpholine → N-(1-adamantyl)morpholine-4-carbothioamide

HRID 436002

Reaktionsgleichung

Reaktionsgleichung von HRID 436002
[C:1]12([N:11]=[C:12]=[S:13])[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH2:2]1)[CH2:8]2.[NH:14]1[CH2:19][CH2:18][O:17][CH2:16][CH2:15]1>CCOCC>[C:1]12([NH:11][C:12]([N:14]3[CH2:19][CH2:18][O:17][CH2:16][CH2:15]3)=[S:13])[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH2:2]1)[CH2:8]2

Komponenten

4

Edukt 2

HCID 8083MorpholineHCID 107279Adamantyl isothiocyanate

Produkt 1

HCID 2828003N-(1-adamantyl)morpholine-4-carbothioamide

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 3283Diethyl EtherLösungsmittel

Versuchsvorschrift

The thiourea is prepared by reacting 5.0 g. (0.026 mole) of 1-adamantyl isothiocyanate with 2.5 g. (0.029 mole) of morpholine in 250 ml. of ether for ca. 1 hr. at room temperature. The solid which separates is collected and combined with additional compound from concentration of ether filtrate to a small volume: 6.65 g. (91 percent), m.p. 145-147. The analytical sample is recrystallized from ether, m.p. 148.

Aufarbeitung

  1. customat room temperature
  2. customThe solid which separates is collected
  3. customThe analytical sample is recrystallized from ether

Quellen und Nachweise

ORD-Eintrag
ord-6912602631aa45beb0219a09ad070591
Quelldatensatz
uspto-grants-1977_02
Patentnummer
US04007181

Verknüpfte Notizen

Wird geladen…