Hydrochloric Acid → 1-(2-Pentylidenehydrazino)-3,4-dihydroisoquinoline

HRID 436433

Reaktionsgleichung

Reaktionsgleichung von HRID 436433
[CH:1](=O)[CH2:2][CH2:3][CH2:4][CH3:5].[NH:7]([C:9]1[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[CH2:12][CH2:11][N:10]=1)[NH2:8].Cl>CCOCC>[CH:1](=[N:8][NH:7][C:9]1[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[CH2:12][CH2:11][N:10]=1)[CH2:2][CH2:3][CH2:4][CH3:5]

Komponenten

5

Edukt 3

HCID 313Hydrochloric AcidHCID 8063PentanalHCID 123490411-Hydrazinyl-3,4-dihydroisoquinoline

Produkt 1

HCID 570944031-(2-Pentylidenehydrazino)-3,4-dihydroisoquinoline

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 3283Diethyl EtherLösungsmittel

Versuchsvorschrift

Valeraldehyde (5.14 g.) was added to a refluxing solution of 1-hydrazino-3,4-dihydroisoquinoline (8 g.) in ether (300 ml.). The mixture was allowed to stand (for 45 min.) at room temperature. Ethereal hydrochloric acid was added. Recrystallization of the resulting solid from ethanol-ether gave 1-(2-pentylidenehydrazino)-3,4-dihydroisoquinoline (I: X=CH3 (CH2)3, X'=Y=Y'=Z=Z'=H) hydrochloride in two crops (11.6 g. and 0.2 g., m.p. 147°-148° C.).

Aufarbeitung

  1. custom(for 45 min.)
  2. customat room temperature
  3. customRecrystallization of the resulting solid from ethanol-ether

Quellen und Nachweise

ORD-Eintrag
ord-044fc138a3be4b3e90b4e14608d19a88
Quelldatensatz
uspto-grants-1977_02
Patentnummer
US04009170

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