Magnesium Hydroxide → 2-Hydroxyimino-2-(1,2,5-thiadiazol-3-yl)acetic acid

Reaktionsgleichung

[S:1]1[N:5]=[CH:4][C:3]([C:6](=O)[C:7]([OH:9])=[O:8])=[N:2]1.Cl.[NH2:12][OH:13].[OH-].[Mg+2].[OH-]>>[OH:13][N:12]=[C:6]([C:3]1[CH:4]=[N:5][S:1][N:2]=1)[C:7]([OH:9])=[O:8]

Komponenten

Edukt 3

HCID 73981Magnesium Hydroxide

HCID 443297Hydroxyamine hydrochloride

HCID 12906559(1,2,5-Thiadiazol-3-yl)glyoxylic acid

Produkt 1

HCID 1361386132-Hydroxyimino-2-(1,2,5-thiadiazol-3-yl)acetic acidAusbeute 97,1 %

Versuchsvorschrift

2-(1,2,5-Thiadiazol-3-yl)glyoxylic acid (7.4 g.) and hydroxylamine hydrochloride (3.1 g.) were reacted in the presence of magnesium hydroxide (4.7 g.) according to a similar manner to that of Example 6(a)(3) to give 2-hydroxyimino-2-(1,2,5-thiadiazol-3-yl)acetic acid (syn isomer) (7.5 g.).

Quellen und Nachweise

ORD-Eintrag: ord-421e31a4612040f7a2d1ab52b5041242
Quelldatensatz: uspto-grants-1981_04
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US04263291

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