Oxalyl chloride → Methyl 9-chloro-9-oxononanoate
Reaktionsgleichung
[C:1](Cl)(=O)[C:2]([Cl:4])=[O:3].[CH3:7][O:8][C:9](=[O:20])[CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15]CC(O)=O>C(Cl)(Cl)Cl>[CH3:7][O:8][C:9]([CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:1][C:2]([Cl:4])=[O:3])=[O:20]Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Reaktionsbedingungen
- Temperatur
- 50 °C
Versuchsvorschrift
In a separate process, 23.9 g of azelaic monomethylester was dissolved in 30 ml chloroform. Oxalylchloride (15 ml) was added, all at once, and the mixture refluxed 2 hours at 50° C. The mixture was cooled; excess solvent and oxalylchloride were evaporated. After distillation, 25.8 g of CH3OCO(CH2)7COCl was obtained.
Aufarbeitung
- temperatureThe mixture was cooled
- customexcess solvent and oxalylchloride were evaporated
- distillationAfter distillation
Quellen und Nachweise
- ORD-Eintrag
- ord-e70b7d36c96148e3b9e913f07b19395b
- Quelldatensatz
- uspto-grants-1985_10
- Patentnummer
- US04544668
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