Propylene Oxide → N-Chlorophthalimide

HRID 46729

Reaktionsgleichung

Reaktionsgleichung von HRID 46729
[C:1]1(=[O:11])[NH:5][C:4](=[O:6])[C:3]2=[CH:7][CH:8]=[CH:9][CH:10]=[C:2]12.C1OC1C.C(N(C(C)C)CC)(C)C.[Cl:25]Cl>C(Cl)Cl>[Cl:25][N:5]1[C:1](=[O:11])[C:2]2=[CH:10][CH:9]=[CH:8][CH:7]=[C:3]2[C:4]1=[O:6]

Komponenten

6

Edukt 4

HCID 6378Propylene OxideHCID 6809PhthalimideHCID 24526ChlorineHCID 81531Diisopropylethylamine

Produkt 1

HCID 18997N-Chlorophthalimide

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

To 150 ml. of dry methylene chloride were added 7.35 g. (0.05 mole) of phthalimide followed by 17.5 ml. (5 equiv.) of propylene oxide and 0.065 g. (0.5 mmoles) of diisopropylethylamine. The mixture was cooled to 0° C. and saturated with chlorine. The mixture was stirred for about 24 hours to provide approximately 50% conversion to N-chlorophthalimide.

Quellen und Nachweise

ORD-Eintrag
ord-30bcf861e6db4b1091088b181ae54e82
Quelldatensatz
uspto-grants-1979_11
Patentnummer
US04175082

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