Methanethiol → Ethyl 2-[(methylsulfanyl)methyl]prop-2-enoate

HRID 46925

Reaktionsgleichung

Reaktionsgleichung von HRID 46925
[CH3:1][SH:2].[Na].[CH2:4]([O:6][C:7](=[O:12])[C:8]([CH2:10]Br)=[CH2:9])[CH3:5]>C(O)C.O>[CH2:4]([O:6][C:7](=[O:12])[C:8]([CH2:10][S:2][CH3:1])=[CH2:9])[CH3:5]

Komponenten

6

Edukt 3

HCID 878MethanethiolHCID 3106202-(Bromomethyl)acrylic acid ethyl esterHCID 5360545Sodium

Produkt 1

HCID 12463627Ethyl 2-[(methylsulfanyl)methyl]prop-2-enoate

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 702EthanolLösungsmittel2×HCID 962WaterLösungsmittel

Versuchsvorschrift

A solution of methylmercaptan (4.8 g.) and sodium (2.3 g.) in absolute ethanol (75 ml.) is added dropwise to a solution of ethyl-2-bromomethylacrylate (19.3 g.) in ethanol (25 ml.). After two hours, it is diluted with water (400 ml.) and extracted with methylene chloride. The organic layer is dried and concentrated to dryness in vacuo to yield ethyl-2-methylthiomethylacrylate.

Aufarbeitung

  1. extractionextracted with methylene chloride
  2. customThe organic layer is dried
  3. concentrationconcentrated to dryness in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-ef169ab13b9c4ed390f40d30a51c76c2
Quelldatensatz
uspto-grants-1979_11
Patentnummer
US04175199

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