Methanethiol → Ethyl 2-[(methylsulfanyl)methyl]prop-2-enoate
Reaktionsgleichung
[CH3:1][SH:2].[Na].[CH2:4]([O:6][C:7](=[O:12])[C:8]([CH2:10]Br)=[CH2:9])[CH3:5]>C(O)C.O>[CH2:4]([O:6][C:7](=[O:12])[C:8]([CH2:10][S:2][CH3:1])=[CH2:9])[CH3:5]Komponenten
6
Edukt 3
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 2
Versuchsvorschrift
A solution of methylmercaptan (4.8 g.) and sodium (2.3 g.) in absolute ethanol (75 ml.) is added dropwise to a solution of ethyl-2-bromomethylacrylate (19.3 g.) in ethanol (25 ml.). After two hours, it is diluted with water (400 ml.) and extracted with methylene chloride. The organic layer is dried and concentrated to dryness in vacuo to yield ethyl-2-methylthiomethylacrylate.
Aufarbeitung
- extractionextracted with methylene chloride
- customThe organic layer is dried
- concentrationconcentrated to dryness in vacuo
Quellen und Nachweise
- ORD-Eintrag
- ord-4a61041afbef48b3896e65e216918e56
- Quelldatensatz
- uspto-grants-1979_11
- Patentnummer
- US04176235
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