6-fluoro-4-oxo-4H-chromene-2-carboxylic acid → 6-Fluoro-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid
Reaktionsgleichung
[F:1][C:2]1[CH:3]=[CH:4][C:5]2[O:10][C:9]([C:11]([OH:13])=[O:12])=[CH:8][C:7](=O)[C:6]=2[CH:15]=1>[Pd].C(O)(=O)C>[F:1][C:2]1[CH:3]=[CH:4][C:5]2[O:10][CH:9]([C:11]([OH:13])=[O:12])[CH2:8][CH2:7][C:6]=2[CH:15]=1Komponenten
4
Edukt 1
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 2
Versuchsvorschrift
6-Fluoro-4-oxo-4H-1-benzopyran-2-carboxylic acid (III) was reacted with 10% palladium on carbon in acetic acid as solvent under hydrogen atmosphere to give 6-fluoro-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid (IV) as shown in Reaction-2 given below by a known process (U.S. Pat. No. 4,654,362).
Quellen und Nachweise
- ORD-Eintrag
- ord-c3f1bd3ca7244b88adb4572fc6b92ce9
- Quelldatensatz
- uspto-grants-2014_01
- Patentnummer
- US08633241B2
Notizen zur Reaktion
Wird geladen…