Acetic Acid → 2,6-Dihydroxyethylaminotoluene

HRID 484265Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 484265
ClCCON[C:6]([NH:8][C:9]1[CH:14]=[CH:13][CH:12]=[C:11]([NH:15][C:16](=O)NOCCCl)[C:10]=1[CH3:23])=O.[OH-:24].[K+].[C:26]([OH:29])(=O)C.[CH3:30]O>O>[OH:24][CH2:30][CH2:16][NH:15][C:11]1[CH:12]=[CH:13][CH:14]=[C:9]([NH:8][CH2:6][CH2:26][OH:29])[C:10]=1[CH3:23]

Komponenten

6

Edukt 4

HCID 176Acetic AcidHCID 887MethanolHCID 14797Potassium HydroxideHCID 19746917HCID 19746917, Verbindung

Produkt 1

HCID 101305242,6-Dihydroxyethylaminotoluene

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Reaktionsbedingungen

Temperatur
75 °C

Versuchsvorschrift

33.5 g of the 2,6-bis(β-chloroethoxycarbamoylamino)toluene obtained above under the 1st stage are initially introduced into the reaction vessel in 200 ml of water and 30 ml of methanol. The reaction mixture is heated to 75° C. and 70 g of 50% strength potassium hydroxide solution are added dropwise in the course of one hour. After the mixture has been subsequently stirred at 60° C. for 21/2 hours, the pH is brought to 8.0 with glacial acetic acid and the reaction mixture is cooled slowly. The product which has precipitated is filtered off with suction, washed with water, and dried at 50° C. in a vacuum cabinet.

Aufarbeitung

  1. temperaturethe reaction mixture is cooled slowly
  2. customThe product which has precipitated
  3. filtrationis filtered off with suction
  4. washwashed with water
  5. customdried at 50° C. in a vacuum cabinet

Quellen und Nachweise

ORD-Eintrag
ord-bf71a19806ae4cf2853e2b718c4b1e1e
Quelldatensatz
uspto-grants-1993_07
Patentnummer
US05230710

Notizen zur Reaktion

Wird geladen…