Diethylene Glycol Monomethyl Ether → HCID 131728281, Verbindung

HRID 502487Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 502487
[CH3:1][C@@H:2]1[O:9]C(=O)[C@H](C)[O:5][C:3]1=[O:4].[CH3:11][O:12][CH2:13][CH2:14][O:15][CH2:16][CH2:17][OH:18].[C:19]([OH:24])(=[O:23])[C@H:20]([CH3:22])[OH:21].C[C@H]1OC(=O)[C@@H](C)OC1=O.[CH3:35][O:36][CH2:37][CH2:38][O:39][CH2:40][CH2:41][OH:42].CCCCC(C([O-])=O)CC.CCCCC(C([O-])=O)CC.[Sn+2]>>[CH3:11][O:12][CH2:13][CH2:14][O:15][CH2:16][CH2:17][OH:18].[C:3]([OH:5])(=[O:4])[C@H:2]([CH3:1])[OH:9].[CH3:35][O:36][CH2:37][CH2:38][O:39][CH2:40][CH2:41][OH:42].[C:19]([OH:24])(=[O:23])[C@@H:20]([CH3:22])[OH:21]

Komponenten

7

Edukt 5

HCID 8134Diethylene Glycol Monomethyl EtherHCID 93182-ethylhexanoic acid tin(II) saltHCID 107983Lactide, L-HCID 5325924D,D-DilactideHCID 131728281HCID 131728281, Verbindung

Produkt 2

HCID 131728281HCID 131728281, VerbindungHCID 131728282HCID 131728282, Verbindung

Versuchsvorschrift

Ringopening polymerization of lactide (L-lactide for system (A) and D-lactide for system B, each 5 g) was carried out using 2-(2-methoxyethoxy)ethanol (MEE, 0.556 g) as an initiator, and stannous octoate (0.093 g) as the catalyst. The polymerization was carried out in the melt at 130° C. for four hours to yield MEE-L-lactic acid oligomer (A) and MEE-D-lactic acid oligomer (B). FIG. 1 shows the reaction scheme for the synthesis of dex-lactate (8), in which the DP is the degree of polymerization and DS is the degree of substitution (number of lactic acid oligomers per 100 glucopyranose units of dextran.

Quellen und Nachweise

ORD-Eintrag
ord-29aa9c7e73964c1c965d400d8b79f949
Quelldatensatz
uspto-grants-2010_08
Patentnummer
US07776359B1

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