Triethylamine → Ethyl [(phenoxycarbonyl)oxy]acetate

HRID 504064

Reaktionsgleichung

Reaktionsgleichung von HRID 504064
Cl[C:2]([O:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)=[O:3].[C:11]([O:15][CH2:16][CH3:17])(=[O:14])[CH2:12][OH:13].C(N(CC)CC)C>C1(C)C=CC=CC=1>[O:4]([C:2]([O:13][CH2:12][C:11]([O:15][CH2:16][CH3:17])=[O:14])=[O:3])[C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1

Komponenten

5

Edukt 3

HCID 8471TriethylamineHCID 12184Ethyl GlycolateHCID 15891Phenyl chloroformate

Produkt 1

HCID 12094709Ethyl [(phenoxycarbonyl)oxy]acetateAusbeute 92,8 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1140TolueneLösungsmittel

Versuchsvorschrift

13.5 ml (105.6 mmol) of phenyl chloroformate are added, dropwise, at ambient temperature to a solution of 10 g (96.15 mmol) of ethyl glycolate and 27 ml (192.3 mmol) of triethylamine in 20 ml of toluene and the mixture is stirred at ambient temperature for 2 h. The salt formed is separated and the filtrate is concentrated under reduced pressure to obtain 20 g of oily product, which are used without modification in the following step.

Aufarbeitung

  1. customThe salt formed
  2. customis separated
  3. concentrationthe filtrate is concentrated under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-bbd48102c7484f56a47adf9e6ebbdf53
Quelldatensatz
uspto-grants-2010_08
Patentnummer
US07777057B2

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