Diisopropylethylamine → 4-[4-(4-tert-butyl-phenyl)-piperazin-1-yl]-1-[(R)-3-(4-nitro-3-trifluoromethyl-phenylamino)-pyrrolidin-1-yl]-butan-1-one

Reaktionsgleichung

[Li+].[C:2]([C:6]1[CH:11]=[CH:10][C:9]([N:12]2[CH2:17][CH2:16][N:15]([CH2:18][CH2:19][CH2:20][C:21]([O-])=[O:22])[CH2:14][CH2:13]2)=[CH:8][CH:7]=1)([CH3:5])([CH3:4])[CH3:3].F[P-](F)(F)(F)(F)F.CN(C)C(ON1C2C=CC=CC=2N=N1)=[N+](C)C.C(N(C(C)C)CC)(C)C.Cl.[N+:58]([C:61]1[CH:66]=[CH:65][C:64]([NH:67][C@@H:68]2[CH2:72][CH2:71][NH:70][CH2:69]2)=[CH:63][C:62]=1[C:73]([F:76])([F:75])[F:74])([O-:60])=[O:59].[O-2].[Al+3].[O-2].[O-2].[Al+3]>O1CCCC1.CN(C)C=O>[C:2]([C:6]1[CH:7]=[CH:8][C:9]([N:12]2[CH2:17][CH2:16][N:15]([CH2:18][CH2:19][CH2:20][C:21]([N:70]3[CH2:71][CH2:72][C@@H:68]([NH:67][C:64]4[CH:65]=[CH:66][C:61]([N+:58]([O-:60])=[O:59])=[C:62]([C:73]([F:74])([F:76])[F:75])[CH:63]=4)[CH2:69]3)=[O:22])[CH2:14][CH2:13]2)=[CH:10][CH:11]=1)([CH3:4])([CH3:5])[CH3:3]