Water → 1-Butoxy-4,4,5,5-tetrafluoropent-1-en-3-one

HRID 512467Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 512467
[CH:1]([F:9])([F:8])[C:2]([F:7])([F:6])[C:3](Cl)=[O:4].N1C=CC=CC=1.[CH:16]([O:18][CH2:19][CH2:20][CH2:21][CH3:22])=[CH2:17].O>ClCCl>[CH2:19]([O:18][CH:16]=[CH:17][C:3](=[O:4])[C:2]([F:7])([F:6])[CH:1]([F:9])[F:8])[CH2:20][CH2:21][CH3:22]

Komponenten

6

Edukt 4

HCID 962WaterHCID 1049PyridineHCID 8108Butyl vinyl etherHCID 27767442,2,3,3-Tetrafluoropropanoyl chloride

Produkt 1

HCID 911638691-Butoxy-4,4,5,5-tetrafluoropent-1-en-3-one

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel2×

Reaktionsbedingungen

Temperatur
0 °C

Versuchsvorschrift

With stirring and at 0° C., 25.0 g (152 mmol) of 3H-tetrafluoropropionyl chloride—dissolved in 20 ml dichloromethane—were added to a mixture of 14.4 g (182 mmol) of pyridine and 15.2 g (152 mmol) of butyl vinyl ether in 250 ml of dichloromethane. After the addition, stirring was continued at room temperature for another 15 h. 250 ml of water were then added to the mixture, and the organic phase was separated off, dried and concentrated. This gave 12.5 g (36% of theory) of a yellowish oil.

Aufarbeitung

  1. additionAfter the addition
  2. stirringstirring
  3. customthe organic phase was separated off
  4. customdried
  5. concentrationconcentrated

Quellen und Nachweise

ORD-Eintrag
ord-5e56fafd7a5f45a6890f10a5dfa365be
Quelldatensatz
uspto-grants-2015_08
Patentnummer
US09102623B2

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