[Cl:1][C:2]([F:10])([F:9])[C:3]([F:8])([F:7])[C:4](Cl)=[O:5].N1C=CC=CC=1.[CH:17]([O:19][CH2:20][CH2:21][CH2:22][CH3:23])=[CH2:18].O>C(Cl)(Cl)Cl>[CH2:20]([O:19][CH:17]=[CH:18][C:4](=[O:5])[C:3]([F:8])([F:7])[C:2]([Cl:1])([F:10])[F:9])[CH2:21][CH2:22][CH3:23]With stirring and at 0° C., 10.0 g (50.2 mmol) of 3-chlorotetrafluoropropionyl chloride—dissolved in ml of chloroform—were added to a mixture of 3.97 g (50.2 mmol) of pyridine and 5.03 g (50.2 mmol) of butyl vinyl ether in 80 ml of chloroform. After the addition, stirring was continued at room temperature for a further 15 h. 100 ml of water were then added to the mixture, and the organic phase was separated off, dried and concentrated. This gave 10.4 g (78% of theory) of a yellowish oil.
Wird geladen…
