Ammonium Chloride → 6-Methoxybenzo[d]thiazole-2-carboximidamide hydrochloride

HRID 524801

Reaktionsgleichung

Reaktionsgleichung von HRID 524801
[CH3:1][O:2][C:3]1[CH:13]=[CH:12][C:6]2[N:7]=[C:8]([C:10]#[N:11])[S:9][C:5]=2[CH:4]=1.C[O-].[Na+].[Cl-:17].[NH4+:18]>>[ClH:17].[CH3:1][O:2][C:3]1[CH:13]=[CH:12][C:6]2[N:7]=[C:8]([C:10](=[NH:18])[NH2:11])[S:9][C:5]=2[CH:4]=1

Komponenten

4

Edukt 3

HCID 25517Ammonium ChlorideHCID 3421092-Cyano-6-methoxy benzothiazoleHCID 10942334Sodium Methoxide

Produkt 1

HCID 1181076136-Methoxybenzo[d]thiazole-2-carboximidamide hydrochlorideAusbeute 75 %

Versuchsvorschrift

6-methoxybenzo[d]thiazole-2-carbonitrile (1 g, 5.26 mmol) was reacted with sodium methoxide (0.28 g, 5.26 mmol) and ammonium chloride (0.6 g, 11 mmol) according to the procedure as described in Example 61, Step B to give the title compound as a white solid (0.96 g, 75%). The compound was characterized by the following spectroscopic data:

Quellen und Nachweise

ORD-Eintrag
ord-a5da7ede6b604060ad6e1da9b0089605
Quelldatensatz
uspto-grants-2016_05
Patentnummer
US09340538B2

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