Water → HCID 67316267, Verbindung

HRID 533235

Reaktionsgleichung

Reaktionsgleichung von HRID 533235
CS(O[CH2:6][CH2:7][CH2:8][C:9]1[C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)[NH:11][C:10]=1[C:18]([O:20][CH2:21][CH3:22])=[O:19])(=O)=O.[C:23]1([SH:33])[C:32]2[C:27](=[CH:28][CH:29]=[CH:30][CH:31]=2)[CH:26]=[CH:25][CH:24]=1.C(=O)([O-])[O-].[K+].[K+].O>C(#N)C>[C:23]1([S:33][CH2:6][CH2:7][CH2:8][C:9]2[C:17]3[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=3)[NH:11][C:10]=2[C:18]([O:20][CH2:21][CH3:22])=[O:19])[C:32]2[C:27](=[CH:28][CH:29]=[CH:30][CH:31]=2)[CH:26]=[CH:25][CH:24]=1

Komponenten

6

Edukt 4

HCID 962WaterHCID 11430Potassium CarbonateHCID 682591-NaphthalenethiolHCID 87353567HCID 87353567, Verbindung

Produkt 1

HCID 67316267HCID 67316267, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6342AcetonitrileLösungsmittel

Versuchsvorschrift

A mixture of EXAMPLE 10A (42 mg), naphthalene thiol (45 mg), and potassium carbonate (36 mg) in acetonitrile (2 mL) was heated at 80° C. for 3 days. The reaction mixture was poured into water, extracted with dichloromethane and purified by flash chromatography on silica gel with 0-20% ethyl acetate in hexanes.

Aufarbeitung

  1. extractionextracted with dichloromethane
  2. custompurified by flash chromatography on silica gel with 0-20% ethyl acetate in hexanes

Quellen und Nachweise

ORD-Eintrag
ord-e1dfa09626a14fc0925b8340aa0a84fc
Quelldatensatz
uspto-grants-2014_10
Patentnummer
US08853209B2

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