Acetic Acid → HCID 178497322, Verbindung

HRID 533412Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 533412
[OH:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([C:12]([O:14][CH3:15])=[O:13])[CH:10]=2)[N:5]=[CH:4][CH:3]=1.[Cl:16]N1C(=O)CCC1=O.C(O)(=O)C>O>[Cl:16][C:3]1[CH:4]=[N:5][C:6]2[C:11]([C:2]=1[OH:1])=[CH:10][C:9]([C:12]([O:14][CH3:15])=[O:13])=[CH:8][CH:7]=2

Komponenten

5

Edukt 3

HCID 176Acetic AcidHCID 31398ChlorosuccinimideHCID 178497323HCID 178497323, Verbindung

Produkt 1

HCID 178497322HCID 178497322, VerbindungAusbeute 88 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

A mixture of methyl 4-hydroxyquinoline-6-carboxylate (2.07 g), N-chlorosuccinimide (1.36 g), and acetic acid (56 mL) was stirred at room temperature for one day. The reaction mixture was diluted with water, and then, the precipitate was collected by filtration to obtain methyl 3-chloro-4-hydroxyquinoline-6-carboxylate (2.13 g).

Aufarbeitung

  1. filtrationthe precipitate was collected by filtration

Quellen und Nachweise

ORD-Eintrag
ord-6b1b42788d7b4d80a849a9ab49c16cbe
Quelldatensatz
uspto-grants-2014_10
Patentnummer
US08853242B2

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