3-Phenoxybenzyl alcohol → 3-Phenoxybenzaldehyde

HRID 53561

Reaktionsgleichung

Reaktionsgleichung von HRID 53561
[O:1]([C:8]1[CH:9]=[C:10]([CH:13]=[CH:14][CH:15]=1)[CH2:11][OH:12])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>C(Cl)Cl.O=[Mn]=O>[O:1]([C:8]1[CH:9]=[C:10]([CH:13]=[CH:14][CH:15]=1)[CH:11]=[O:12])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Komponenten

4

Edukt 1

HCID 262953-Phenoxybenzyl alcohol

Produkt 1

HCID 382843-PhenoxybenzaldehydeAusbeute 90,1 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 14801Manganese dioxideKatalysator2×HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

To a solution of 1.8 mL (10.3 mmol) of 3-phenoxybenzyl alcohol (Aldrich Chemical Co.) in 20 mL of CH2Cl2 at room temperature was added 1.5 g of powdered 4 Å molecular sieves and 2.5 g of activated MnO2. The resulting suspension was stirred at room temperature for 0.5 h, at which time an additional 2.5 g of MnO2 was added. After stirring at room temperature for 0.5 h the reaction mixture was filtered through celite to give 1.84 g of the aldehyde 125 as an oil. 1H NMR consistent with structure.

Aufarbeitung

  1. additionwas added
  2. filtrationwas filtered through celite

Quellen und Nachweise

ORD-Eintrag
ord-35629b73a3e847de81fee2c3de8bd658
Quelldatensatz
uspto-grants-1997_04
Patentnummer
US05620971

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