Lithium Hydroxide → HCID 13708826, Verbindung

HRID 54169Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 54169
[OH-].[Li+].[CH3:3][C:4](=[CH2:13])/[CH:5]=[CH:6]/[CH2:7][C:8]([O:10]CC)=[O:9]>CO.O1CCCC1.O>[CH3:13][C:4](=[CH2:3])/[CH:5]=[CH:6]/[CH2:7][C:8]([OH:10])=[O:9]

Komponenten

6

Edukt 2

HCID 3939Lithium HydroxideHCID 14524662Ethyl trans-4-methyl-2,4-pentadienecarboxylate

Produkt 1

HCID 13708826HCID 13708826, VerbindungAusbeute 76 %

Reagenzien, Katalysatoren, Lösungsmittel 3

HCID 887MethanolLösungsmittelHCID 962WaterLösungsmittel2×HCID 8028TetrahydrofuranLösungsmittel

Versuchsvorschrift

2.5 g (0.1 mol) of lithium hydroxide are added at 0° C. to 10 g (0.07 mol) of ethyl trans-4-methyl-2,4-pentadienecarboxylate, dissolved in a solvent mixture of 75 ml of methanol, 17 ml of tetrahydrofuran and 2.5 ml of water, and the mixture is stirred for 20 hours at room temperature. After the mixture has been diluted with 200 ml of water, it is extracted once using diethyl ether, and a pH of 1 is established in the aqueous phase at 0° C. using concentrated hydrochloric acid. The mixture is extracted using diethyl ether, the combined organic phases are washed several times with water and saturated sodium chloride solution, and, after drying and concentrating, 6.1 g (76% of theory) of trans-4-methyl-2,4-pentadienecarboxylic acid are obtained. ##STR208##

Aufarbeitung

  1. extractionis extracted once using diethyl ether
  2. customis established in the aqueous phase at 0° C.
  3. extractionThe mixture is extracted
  4. washthe combined organic phases are washed several times with water and saturated sodium chloride solution
  5. customafter drying
  6. concentrationconcentrating

Quellen und Nachweise

ORD-Eintrag
ord-299d8a018f6644f7be2076f3bd417fef
Quelldatensatz
uspto-grants-1997_04
Patentnummer
US05622916

Notizen zur Reaktion

Wird geladen…