Acetic Acid → 2-(4-tert-butylbenzylidene)-3,4-dihydro-1(2H)-naphthalenone

HRID 54587

Reaktionsgleichung

Reaktionsgleichung von HRID 54587
[C:1]1(=[O:11])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3][CH2:2]1.[C:12]([C:16]1[CH:23]=[CH:22][C:19]([CH:20]=O)=[CH:18][CH:17]=1)([CH3:15])([CH3:14])[CH3:13].[OH-].[K+].C(O)(=O)C>CO.O>[C:12]([C:16]1[CH:17]=[CH:18][C:19]([CH:20]=[C:2]2[CH2:3][CH2:4][C:5]3[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=3)[C:1]2=[O:11])=[CH:22][CH:23]=1)([CH3:15])([CH3:13])[CH3:14]

Komponenten

7

Edukt 4

HCID 176Acetic AcidHCID 107241-TetraloneHCID 14797Potassium HydroxideHCID 703244-tert-Butylbenzaldehyde

Produkt 1

HCID 35712132-(4-tert-butylbenzylidene)-3,4-dihydro-1(2H)-naphthalenone

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 887MethanolLösungsmittelHCID 962WaterLösungsmittel

Versuchsvorschrift

A mixture of 3,4-dihydro-1(2H)-naphthalenone (4.5 g) and 4-tert-butylbenzaldehyde (5.0 g) was stirred with a solution of 4% potassium hydroxide in methanol (100 ml) for 64 hours at room temperature. The mixture was neutralised with glacial acetic acid, followed by dilution with water (100 ml). The resulting copious white precipitate was filtered off, washed with water and dried in vacuo to give 2-(4-tert-butylbenzylidene)-3,4-dihydro-1(2H)-naphthalenone.

Aufarbeitung

  1. filtrationThe resulting copious white precipitate was filtered off
  2. washwashed with water
  3. customdried in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-392e6da757734f54a4b9ebfe00572a19
Quelldatensatz
uspto-grants-1997_04
Patentnummer
US05622987

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