1-Hydroxybenzotriazole → (E)-N-[3-(4-chlorophenyl)-2-oxo-tetrahydropyrimidin-1-yl]-3-[6-methoxy-5-(4-methyl-1H-imidazol-1-yl)pyridin-2-yl]acrylamide

Reaktionsgleichung

C(N(C(C)C)CC)(C)C.[NH2:10][N:11]1[CH2:16][CH2:15][CH2:14][N:13]([C:17]2[CH:22]=[CH:21][C:20]([Cl:23])=[CH:19][CH:18]=2)[C:12]1=[O:24].C1C=CC2N(O)N=NC=2C=1.[CH3:35][O:36][C:37]1[N:42]=[C:41](/[CH:43]=[CH:44]/[C:45](O)=[O:46])[CH:40]=[CH:39][C:38]=1[N:48]1[CH:52]=[C:51]([CH3:53])[N:50]=[CH:49]1>CN(C=O)C.C(OCC)(=O)C.C(Cl)CCl>[Cl:23][C:20]1[CH:19]=[CH:18][C:17]([N:13]2[CH2:14][CH2:15][CH2:16][N:11]([NH:10][C:45](=[O:46])/[CH:44]=[CH:43]/[C:41]3[CH:40]=[CH:39][C:38]([N:48]4[CH:52]=[C:51]([CH3:53])[N:50]=[CH:49]4)=[C:37]([O:36][CH3:35])[N:42]=3)[C:12]2=[O:24])=[CH:22][CH:21]=1