Hydrochloric Acid → HCID 178505461, Verbindung

HRID 555814Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 555814
[F:1][C:2]1[CH:3]=[C:4](N)[C:5]([NH2:8])=[CH:6][CH:7]=1.[C:10]([S-:15])(=[S:14])OCC.[K+].O.Cl>CN(C=O)C>[F:1][C:2]1[CH:7]=[CH:6][C:5]2[N:8]=[C:10]([SH:15])[S:14][C:4]=2[CH:3]=1

Komponenten

6

Edukt 4

HCID 313Hydrochloric AcidHCID 962WaterHCID 1645844-Fluorobenzene-1,2-diamineHCID 2735045Potassium ethylxanthate

Produkt 1

HCID 178505461HCID 178505461, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6228DimethylformamideLösungsmittel

Reaktionsbedingungen

Temperatur
95 °C

Versuchsvorschrift

4-Fluorobenzene-1,2-diamine (10.0 g, 0.077 mol) and potassium O-ethyl carbonodithioate (37.1 g, 0.234 mol) were dissolved in dry DMF (150 mL) under nitrogen and heated to 95° C. for 12 h. The reaction was cooled to RT and 200 mL water was added followed by addition of 5N HCl to get precipitates. After stirring for 1 h, the precipitates were collected by filtration, washed with water and dried under vacuum for 2 h. The crude compound was then washed with chloroform and dried to give 6-fluorobenzo[d]thiazole-2-thiol as yellow solid.

Aufarbeitung

  1. temperatureThe reaction was cooled to RT
  2. customto get
  3. customprecipitates
  4. filtrationthe precipitates were collected by filtration
  5. washwashed with water
  6. customdried under vacuum for 2 h
  7. washThe crude compound was then washed with chloroform
  8. customdried

Quellen und Nachweise

ORD-Eintrag
ord-13c7f6e11af743ab90fc114837dfcdf6
Quelldatensatz
uspto-grants-2011_11
Patentnummer
US08053438B2

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