Triethylamine → 1-Fluoro-2-[(trifluoromethyl)sulfanyl]benzene

HRID 573078Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 573078
[F:1][C:2](I)([F:4])[F:3].[F:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[SH:13].C(N(CC)CC)C>CN(C)C=O.O>[F:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[S:13][C:2]([F:4])([F:3])[F:1]

Komponenten

6

Edukt 3

HCID 8471TriethylamineHCID 16843TrifluoroiodomethaneHCID 5202162-Fluorothiophenol

Produkt 1

HCID 470028801-Fluoro-2-[(trifluoromethyl)sulfanyl]benzene

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 962WaterLösungsmittelHCID 6228DimethylformamideLösungsmittel

Versuchsvorschrift

Methyl viologen hydrochloride (1.17 g) in N,N-dimethylformamide (80 mL) at 25° C. was saturated with trifluoromethyl iodide, treated with 2-fluorobenzenethiol (9.7 mL) and triethylamine (20 mL), stirred for 24 hours, diluted with water (240 mL) and extracted with diethyl ether. The extract was washed with 1M aqueous NaOH, saturated ammonium chloride and brine and concentrated.

Aufarbeitung

  1. customat 25° C.
  2. extractionextracted with diethyl ether
  3. washThe extract was washed with 1M aqueous NaOH, saturated ammonium chloride and brine
  4. concentrationconcentrated

Quellen und Nachweise

ORD-Eintrag
ord-720bceb42ff6432cace14bcbaefbb80d
Quelldatensatz
uspto-grants-2015_05
Patentnummer
US09029404B2

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