4-Nitrobenzaldehyde → p-Nitrobenzaldoxime

HRID 580092

Reaktionsgleichung

Reaktionsgleichung von HRID 580092
[N+:1]([C:4]1[CH:11]=[CH:10][C:7]([CH:8]=O)=[CH:6][CH:5]=1)([O-:3])=[O:2].Cl.[NH2:13][OH:14]>CO.O>[N+:1]([C:4]1[CH:11]=[CH:10][C:7]([CH:8]=[N:13][OH:14])=[CH:6][CH:5]=1)([O-:3])=[O:2]

Komponenten

5

Edukt 2

HCID 5414-NitrobenzaldehydeHCID 443297Hydroxyamine hydrochloride

Produkt 1

HCID 96339p-NitrobenzaldoximeAusbeute 94,7 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 887MethanolLösungsmittelHCID 962WaterLösungsmittel2×

Reaktionsbedingungen

Temperatur
30 °C

Versuchsvorschrift

52.9 g (0.35 mol) of p-nitrobenzaldehyde was dissolved in 100 ml of methanol and a solution of 27.8 g (0.38 mol) of hydroxylamine hydrochloride in 35 ml of water was added dropwise over 30 minutes while maintaining the temperature at 30° C. and then, stirred at the same temperature for two hours followed by dilution with 300 ml of water. White crystals deposited were filtered and dried to obtain 55 g of p-nitrobenzaldoxime. Yield 94.7%; M.P. 128°-131° C.

Aufarbeitung

  1. filtrationWhite crystals deposited were filtered
  2. customdried

Quellen und Nachweise

ORD-Eintrag
ord-0f70ebd744a94e19873dae59cefcd4f0
Quelldatensatz
uspto-grants-1988_06
Patentnummer
US04751328

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