4-Nitrobenzaldehyde → p-Nitrobenzaldoxime

HRID 580095Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 580095
[N+:1]([C:4]1[CH:11]=[CH:10][C:7]([CH:8]=O)=[CH:6][CH:5]=1)([O-:3])=[O:2].Cl.[NH2:13][OH:14]>CO.O>[N+:1]([C:4]1[CH:11]=[CH:10][C:7]([CH:8]=[N:13][OH:14])=[CH:6][CH:5]=1)([O-:3])=[O:2]

Komponenten

5

Edukt 2

HCID 5414-NitrobenzaldehydeHCID 443297Hydroxyamine hydrochloride

Produkt 1

HCID 96339p-NitrobenzaldoximeAusbeute 97 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 887MethanolLösungsmittelHCID 962WaterLösungsmittel2×

Reaktionsbedingungen

Temperatur
30 °C

Versuchsvorschrift

151 g (1 mol) of p-nitrobenzaldehyde was dissolved in 350 ml of methanol and an aqueous solution of 80.3 g (1.1 mol) of hydroxylamine hydrochloride in 100 ml of water was added dropwise over 30 minutes while maintaining the temperature at 30° C. Thereafter the mixture was stirred at the same temperature for 2 hours and diluted with 1000 ml of water. White crystals deposited were filtered, washed with water and dried. Thus, 161 g of p-nitrobenzaldoxime was obtained. Yield 97%; M.P. 128°-131° C.

Aufarbeitung

  1. filtrationWhite crystals deposited were filtered
  2. washwashed with water
  3. customdried

Quellen und Nachweise

ORD-Eintrag
ord-00c8a55dd507475c9b69b37b6120058e
Quelldatensatz
uspto-grants-1988_06
Patentnummer
US04751328

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