Water → HCID 10499321, Verbindung

HRID 613017Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 613017
Cl[C:2]1[CH:7]=[C:6]([C:8]2[C:17]3[C:12](=[CH:13][C:14]([O:21][CH3:22])=[C:15]([O:18][CH2:19][CH3:20])[CH:16]=3)[CH:11]=[C:10]([CH2:23][OH:24])[C:9]=2[CH2:25][OH:26])[CH:5]=[CH:4][N:3]=1.O.O.[NH2:29][NH2:30]>>[NH:29]([C:2]1[CH:7]=[C:6]([C:8]2[C:17]3[C:12](=[CH:13][C:14]([O:21][CH3:22])=[C:15]([O:18][CH2:19][CH3:20])[CH:16]=3)[CH:11]=[C:10]([CH2:23][OH:24])[C:9]=2[CH2:25][OH:26])[CH:5]=[CH:4][N:3]=1)[NH2:30]

Komponenten

4

Edukt 3

HCID 962WaterHCID 24654Hydrazine hydrate (1:1)HCID 10738129HCID 10738129, Verbindung

Produkt 1

HCID 10499321HCID 10499321, Verbindung

Versuchsvorschrift

A suspension of 1-(2-chloro-4-pyridyl)-2,3-bis(hydroxymethyl)-6-methoxy-7-ethoxynaphthalene (16.0 g) in hydrazine hydrate (50 ml) is refluxed for four hours. The mixture is cooled to room temperature, and then thereto is added water. The precipitated crystals are collected by filtration, washed with water, and dried to give 1-(2-hydrazino-4-pyridyl)-2,3-bis(hydroxymethyl)-6-methoxy-7-ethoxynaphthalene (14.5 g).

Aufarbeitung

  1. temperatureis refluxed for four hours
  2. filtrationThe precipitated crystals are collected by filtration
  3. washwashed with water
  4. customdried

Quellen und Nachweise

ORD-Eintrag
ord-96d05e891c3f4fa4bc20fbd18cc4dea9
Quelldatensatz
uspto-grants-1999_12
Patentnummer
US06005106

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