Etidronic Acid → ZINC etidronate

HRID 615828

Reaktionsgleichung

Reaktionsgleichung von HRID 615828
[O-2].[Zn+2:2].[CH3:3][C:4]([P:10]([OH:13])([OH:12])=[O:11])([P:6]([OH:9])([OH:8])=[O:7])[OH:5]>O>[Zn:2].[CH3:3][C:4]([P:10]([OH:13])([OH:12])=[O:11])([P:6]([OH:9])([OH:8])=[O:7])[OH:5]

Komponenten

4

Edukt 2

HCID 3305Etidronic Acid2×HCID 3007857Zinc Oxide3×

Produkt 1

HCID 86739934ZINC etidronateAusbeute 121,2 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Reaktionsbedingungen

Temperatur
70 °C

Versuchsvorschrift

184.8 grams (2.28 moles) zinc oxide was slurried at 20 percent by weight in water and heated to 70° C. An aqueous solution containing 316 grams (1.52 moles) etidronic acid was diluted to 20 percent by weight and heated to 70° C. The zinc oxide slurry was pumped into the etidronic acid solution over 45 minutes with continuous stirring of both the slurry and the solution. A precipitate formed after the addition of about 20 percent of the zinc oxide. The slurry formed was stirred for 4 hours at 60°-70° C. to allow the salt-forming reaction to take place. The slurry was then cooled and filtered on a Buchner funnel. The solid obtained was washed 4 times with distilled water using 2 liters of water each time to wash the salt free of etidronic acid. The wet filter cake was broken up and oven dried at 110° C. to obtain about 500 grams of zinc etidronate as a while solid with needle-like crystals. The solubility of the zinc etidronate was measured by slurrying it in distilled water, centrifuging and measuring the dissolved metal ion content. The metal ion content was 0.165 grams per liter, indicating a pigment solubility of 0.5 grams per liter.

Aufarbeitung

  1. additionwas diluted to 20 percent by weight
  2. temperatureheated to 70° C
  3. customA precipitate formed
  4. customThe slurry formed
  5. stirringwas stirred for 4 hours at 60°-70° C.
  6. customthe salt-forming reaction
  7. temperatureThe slurry was then cooled
  8. filtrationfiltered on a Buchner funnel
  9. customThe solid obtained
  10. washwas washed 4 times with distilled water using 2 liters of water each time
  11. washto wash the salt free of etidronic acid
  12. customdried at 110° C.

Quellen und Nachweise

ORD-Eintrag
ord-2301b509c5564f29b10bf17b3e170584
Quelldatensatz
uspto-grants-1985_02
Patentnummer
US04501615

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