Hydrogen Bromide → 2-Bromo-1-(6-methylpyridin-3-yl)ethanone hydrobromide

HRID 633747

Reaktionsgleichung

Reaktionsgleichung von HRID 633747
[CH3:1][C:2]1[N:7]=[CH:6][C:5]([C:8](=[O:10])[CH3:9])=[CH:4][CH:3]=1.[BrH:11].BrBr>C(O)(=O)C>[BrH:11].[Br:11][CH2:9][C:8]([C:5]1[CH:6]=[N:7][C:2]([CH3:1])=[CH:3][CH:4]=1)=[O:10]

Komponenten

5

Edukt 3

HCID 260Hydrogen BromideHCID 24408BromineHCID 952923-Acetyl-6-methylpyridine

Produkt 1

HCID 454805112-Bromo-1-(6-methylpyridin-3-yl)ethanone hydrobromide

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 176Acetic AcidLösungsmittel

Versuchsvorschrift

500 mg (3.59 mmol) of 1-(6-methylpyrid-3-yl)ethanone, 590 μl (3.59 mmol) of hydrobromic acid, 204 μl (3.95 mmol) of bromine and 10 mL of glacial acetic acid were used in the reaction. After precipitation with ethyl ether and filtration, 1.02 g of 2-bromo-1-(6-methylpyrid-3-yl)ethanone hydrobromide are obtained, the characteristics of which are as follows:

Aufarbeitung

  1. customAfter precipitation
  2. filtrationwith ethyl ether and filtration, 1.02 g of 2-bromo-1-(6-methylpyrid-3-yl)ethanone hydrobromide
  3. customare obtained

Quellen und Nachweise

ORD-Eintrag
ord-eee58b6607064dc58e5a858551127640
Quelldatensatz
uspto-grants-2016_04
Patentnummer
US09321790B2

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