Water → 1,2-Diphenylethane-1,2-dione (2-methylphenyl)-hydrazone

HRID 643288

Reaktionsgleichung

Reaktionsgleichung von HRID 643288
Cl.[CH3:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[NH:9][NH2:10].[C:11]1([C:17](=O)[C:18]([C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)=[O:19])[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1.O>C(O)(=O)C>[CH3:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[NH:9][N:10]=[C:17]([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)[C:18]([C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1)=[O:19]

Komponenten

5

Edukt 3

HCID 962WaterHCID 8651BenzilHCID 71554o-Tolylhydrazinium(1+) chloride

Produkt 1

HCID 866089501,2-Diphenylethane-1,2-dione (2-methylphenyl)-hydrazoneAusbeute 101,8 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 176Acetic AcidLösungsmittel

Versuchsvorschrift

A mixture of 2-methylphenyl hydrazine hydrochloride (0.79 g, 5.0 mmol) and 1,2-diphenyl-ethane-1,2-dione (1.05 g, 5 mmol) in 20 mL of glacial acetic acid was refluxed for 30 min. The reaction was poured into water and extracted with ethyl acetate. The combined organics was dried over MgSO4 and concentrated to give 1.6 gram of 1,2-diphenylethane-1,2-dione (2-methylphenyl)-hydrazone as an orange solid. MS (ESI) m/z 315 ([M+H]+);

Aufarbeitung

  1. temperaturewas refluxed for 30 min
  2. extractionextracted with ethyl acetate
  3. dry with materialThe combined organics was dried over MgSO4
  4. concentrationconcentrated

Quellen und Nachweise

ORD-Eintrag
ord-6a58b27c657646648bfad80242fd5e7e
Quelldatensatz
uspto-grants-2010_04
Patentnummer
US07700595B2

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