1-Methylimidazole → HCID 70387076, Verbindung

HRID 64658Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 64658
[Br:1][CH2:2][C:3]([C:5]1[CH:10]=[CH:9][C:8]([CH3:11])=[CH:7][C:6]=1[CH3:12])=[O:4].[CH3:13][N:14]1[CH:18]=[CH:17][N:16]=[CH:15]1>C(OCC)C>[Br-:1].[CH3:13][NH+:14]1[CH:18]=[CH:17][N:16]([CH2:2][C:3]([C:5]2[CH:10]=[CH:9][C:8]([CH3:11])=[CH:7][C:6]=2[CH3:12])=[O:4])[CH2:15]1

Komponenten

4

Edukt 2

HCID 13901-MethylimidazoleHCID 20634502-Bromo-1-(2,4-dimethylphenyl)ethanone

Produkt 1

HCID 70387076HCID 70387076, VerbindungAusbeute 51 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 3283Diethyl EtherLösungsmittel

Versuchsvorschrift

A solution of 4.76 g (0.021 mol) of 1-bromo-2-(2,4-dimethylphenyl)-2-oxoethane and 1.76 g (0.021 mol) of 1-methylimidazole in 50 ml of diethyl ether was stirred at room temperature for approximately 21 hours. The reaction solvent was decanted and the residue was washed with diethyl ether. The residue was recrystallized from acetonitrile/ethyl acetate to afford 3.32 g of the title product as white crystals. (51% yield) mp=179°-181° C.

Aufarbeitung

  1. customThe reaction solvent was decanted
  2. washthe residue was washed with diethyl ether
  3. customThe residue was recrystallized from acetonitrile/ethyl acetate

Quellen und Nachweise

ORD-Eintrag
ord-9b4d12cf9aeb42d6958889fdc6c42afe
Quelldatensatz
uspto-grants-1986_09
Patentnummer
US04609670

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