Water → 2,2,4,4-Tetramethylpentan-3-amine

HRID 648342Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 648342
[C:1]([C:5](=[NH:10])[C:6]([CH3:9])([CH3:8])[CH3:7])([CH3:4])([CH3:3])[CH3:2].[H-].[Al+3].[Li+].[H-].[H-].[H-].O.[OH-].[Na+]>CCOCC>[CH3:2][C:1]([CH3:4])([CH:5]([NH2:10])[C:6]([CH3:9])([CH3:8])[CH3:7])[CH3:3]

Komponenten

6

Edukt 4

HCID 962Water2×HCID 14798Sodium HydroxideHCID 27556322,2,4,4-Tetramethyl-3-pentanone ImineHCID 21226445Aluminium lithium hydride

Produkt 1

HCID 131658882,2,4,4-Tetramethylpentan-3-amine

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 3283Diethyl EtherLösungsmittel2×

Versuchsvorschrift

The imine (14 g.) in dry ether (50 ml.) was added to a suspension of lithium aluminum hydride (1.7 g.) in dry ether (50 ml.). The mixture was stirred at room temperature for 24 hours, refluxed two hours and cooled. Water (1.7 ml.), 15% sodium hydroxide solution (5 ml.) and water (5 ml.) were added cautiously in succession, the mixture filtered, concentrated and the residue distilled to afford the desired amine, b.p. 79°-81° C./40 mm.

Aufarbeitung

  1. temperaturerefluxed two hours
  2. temperaturecooled
  3. filtrationthe mixture filtered
  4. concentrationconcentrated
  5. distillationthe residue distilled

Quellen und Nachweise

ORD-Eintrag
ord-1286bf00543244e99c6beb3064d7e232
Quelldatensatz
uspto-grants-1983_10
Patentnummer
US04411925

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