Benzaldehyde → 5-Benzylidenehydantoin

HRID 652564

Reaktionsgleichung

Reaktionsgleichung von HRID 652564
NCC(O)=O.C(=O)([O-])[O-].[Na+].[Na+].[CH:12](=O)[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1.[NH:20]1[CH2:26][C:24](=[O:25])[NH:23][C:21]1=[O:22]>O>[CH:12](=[C:26]1[NH:20][C:21](=[O:22])[NH:23][C:24]1=[O:25])[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

Komponenten

6

Edukt 4

HCID 240BenzaldehydeHCID 750GlycineHCID 10006HydantoinHCID 10340Sodium Carbonate

Produkt 1

HCID 978575-BenzylidenehydantoinAusbeute 88,3 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

A 37.5 g amount of glycine and 26.5 g of sodium carbonate were dissolved in 200 ml of water in the flask. Then, 53.0 g of benzaldehyde and 50.0 g of hydantoin were added to the resultant solution. The mixture was allowed to react at a temperature of 100° C. for 1 hour while stirring. During the reaction, the pH of the reaction mixture was 9.7 to 9.4. After cooling, the precipitated 5-benzylidene hydantoin was separated and recovered from the reaction mixture. Thus, 83.0 g of 5-benzylidene hydantoin was obtained. The yield was 88% based on the hydantoin.

Aufarbeitung

  1. customto react at a temperature of 100° C. for 1 hour
  2. customDuring the reaction
  3. temperatureAfter cooling
  4. customthe precipitated 5-benzylidene hydantoin was separated
  5. customrecovered from the reaction mixture

Quellen und Nachweise

ORD-Eintrag
ord-c90b895d8587415dabf3dde44a8eac9d
Quelldatensatz
uspto-grants-1987_06
Patentnummer
US04672127

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