Tobramycin Sulphate Salt → Tobramycin

HRID 654729

Reaktionsgleichung

Reaktionsgleichung von HRID 654729
[CH2:1]1[C@@H:6]([NH2:7])[C@H:5]([O:8][C@H:9]2[O:14][C@H:13]([CH2:15][OH:16])[C@@H:12]([OH:17])[C@H:11]([NH2:18])[C@H:10]2[OH:19])[C@@H:4]([OH:20])[C@H:3]([O:21][C@H:22]2[O:27][C@H:26]([CH2:28][NH2:29])[C@@H:25]([OH:30])[CH2:24][C@H:23]2[NH2:31])[C@H:2]1[NH2:32].OS(O)(=O)=O>O>[CH2:1]1[C@@H:6]([NH2:7])[C@H:5]([O:8][C@H:9]2[O:14][C@H:13]([CH2:15][OH:16])[C@@H:12]([OH:17])[C@H:11]([NH2:18])[C@H:10]2[OH:19])[C@@H:4]([OH:20])[C@H:3]([O:21][C@H:22]2[O:27][C@H:26]([CH2:28][NH2:29])[C@@H:25]([OH:30])[CH2:24][C@H:23]2[NH2:31])[C@H:2]1[NH2:32]

Komponenten

3

Edukt 1

HCID 62005Tobramycin Sulphate Salt

Produkt 1

HCID 36294Tobramycin

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

Foam wound materials containing tobramycin sulfate were prepared as shown in Example 1. Once the materials were placed onto grid supports they were maintained at room temperature and covered with a foil wrap. Every 12 hours for nine days, 5 ml of water was applied onto the foam bandage materials and eluent was collected. Two ml samples containing SDMC-entrapped tobramycin were assayed for tobramycin antibiotic activity using standard antimicrobial assays. The results are shown in Table IX.

Aufarbeitung

  1. customwere prepared
  2. customwas collected
  3. additionTwo ml samples containing SDMC-entrapped tobramycin

Quellen und Nachweise

ORD-Eintrag
ord-905e4c58834248fdad85170d3c81d257
Quelldatensatz
uspto-grants-1992_07
Patentnummer
US05133965

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