Ethyl ketone → 2-Cyclohexen-1-one, 2,5,6-trimethyl-

HRID 65803

Reaktionsgleichung

Reaktionsgleichung von HRID 65803
CO[CH:3]([CH3:7])[CH2:4][CH:5]=[O:6].[CH2:8]([C:10]([CH2:12]C)=O)[CH3:9].[CH3:14][O-].[Na+]>CO>[CH3:14][C:4]1[C:5](=[O:6])[CH:8]([CH3:9])[CH:10]([CH3:12])[CH2:7][CH:3]=1

Komponenten

5

Edukt 3

HCID 7288Ethyl ketoneHCID 980403-MethoxybutyraldehydeHCID 10942334Sodium Methoxide

Produkt 1

HCID 892642-Cyclohexen-1-one, 2,5,6-trimethyl-Ausbeute 56 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Versuchsvorschrift

102 g of β-methoxybutyraldehyde is dripped in the course of one hour into a mixture of 500 g of diethyl ketone and 10 g of a 30% solution of sodium methylate in methanol which is boiling under reflux. The whole is then heated for another hour under reflux. The reaction mixture is processed as described in Example 2. 77 g of 2,5,6-trimethyl-2-cyclohexen-1-one is obtained, i.e. a 56% yield with reference to β-methoxybutyraldehyde.

Aufarbeitung

  1. temperatureunder reflux
  2. temperatureThe whole is then heated for another hour
  3. temperatureunder reflux

Quellen und Nachweise

ORD-Eintrag
ord-9c14c87cead5429790577056f90c7ce5
Quelldatensatz
uspto-grants-1978_12
Patentnummer
US04128728

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