Chlorotrifluoroethylene → 4-(1,1,2-Trifluoro-2-chloroethylthio)toluene

HRID 66646

Reaktionsgleichung

Reaktionsgleichung von HRID 66646
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([SH:8])=[CH:4][CH:3]=1.[OH-].[K+].[F:11][C:12]([F:16])=[C:13]([F:15])[Cl:14].[OH-].[Na+]>O.CC(C)=O>[F:11][C:12]([F:16])([S:8][C:5]1[CH:6]=[CH:7][C:2]([CH3:1])=[CH:3][CH:4]=1)[CH:13]([F:15])[Cl:14]

Komponenten

7

Edukt 4

HCID 6594ChlorotrifluoroethyleneHCID 78114-MethylbenzenethiolHCID 14797Potassium HydroxideHCID 14798Sodium Hydroxide

Produkt 1

HCID 205306464-(1,1,2-Trifluoro-2-chloroethylthio)toluene

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 180AcetoneLösungsmittelHCID 962WaterLösungsmittel

Versuchsvorschrift

A hot solution (60° C.) of 248 g (2 moles) of 4-methylthiophenol, 44.8 g of 85% potassium hydroxide, and 280 ml of acetone were placed in an autoclave. An amount of 256 g (2.2 moles) of trifluorochloroethylene was introduced in 1 h under pressure with agitation at 50°-55° C. After 1 h the reaction mixture was poured out in a solution of 1200 ml of water and 80 g (2 moles) of sodium hydroxide. The final product was extracted with ether, the ether solution was dried, and the solvent was evaporated. The residual oil was distilled at 120° C./1 mm.

Aufarbeitung

  1. extractionThe final product was extracted with ether
  2. dry with materialthe ether solution was dried
  3. customthe solvent was evaporated
  4. distillationThe residual oil was distilled at 120° C./1 mm

Quellen und Nachweise

ORD-Eintrag
ord-ec581c965b27422db5959ac0e15fb3e1
Quelldatensatz
uspto-grants-1982_08
Patentnummer
US04342825

Verknüpfte Notizen

Wird geladen…