Hydrochloric Acid → 4,4-Dimethylcyclohexane-1-carbaldehyde

HRID 70266Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 70266
[CH3:1][C:2]1([CH3:11])[CH2:7][CH2:6][C:5](=[CH:8][O:9]C)[CH2:4][CH2:3]1.Cl>C1COCC1.C(OCC)C.[Cl-].[Na+].O.O>[CH3:1][C:2]1([CH3:11])[CH2:7][CH2:6][CH:5]([CH:8]=[O:9])[CH2:4][CH2:3]1

Komponenten

7

Edukt 2

HCID 313Hydrochloric AcidHCID 589086674-Methoxymethylene-1,1-dimethyl-cyclohexane

Produkt 1

HCID 222352954,4-Dimethylcyclohexane-1-carbaldehyde

Reagenzien, Katalysatoren, Lösungsmittel 4

HCID 962WaterLösungsmittelHCID 3283Diethyl EtherLösungsmittelHCID 8028TetrahydrofuranLösungsmittelHCID 57417360Sodium chloride; waterLösungsmittel

Versuchsvorschrift

A solution of (4,4-dimethyl cyclohexylidene)methyl methyl ether (6.7 g, 0.043 mol) in THF (200 mL) containing 6M HCl (aq) (60 mL) was stirred at room temperature for 24 hr. The reaction mixture was diluted with a mixture of ethyl ether, hexanes, brine and water. The mixture was separated and the aqueous phase was extracted with ethyl ether. The combined organic phase was washed with brine, dried over Na2SO4, and concentrated in vacuo, affording 4,4-dimethylcyclohexanecarbaldehyde as a yellow oil, used without further purification.

Aufarbeitung

  1. customThe mixture was separated
  2. extractionthe aqueous phase was extracted with ethyl ether
  3. washThe combined organic phase was washed with brine
  4. dry with materialdried over Na2SO4
  5. concentrationconcentrated in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-cdff3e5f4670424e8ceb6362f31354bf
Quelldatensatz
uspto-grants-2014_09
Patentnummer
US08822518B2

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