Magnesium Stearate → Clonidine

HRID 716609

Reaktionsgleichung

Reaktionsgleichung von HRID 716609
[CH:1]1[CH:6]=[C:5]([Cl:7])[C:4]([NH:8][C:9]2[NH:13][CH2:12][CH2:11][N:10]=2)=[C:3]([Cl:14])[CH:2]=1.Cl.OP([O-])([O-])=O.[Ca+2].C([O-])(=O)CCCCCCCCCCCCCCCCC.[Mg+2].C([O-])(=O)CCCCCCCCCCCCCCCCC>>[CH:1]1[CH:6]=[C:5]([Cl:7])[C:4]([NH:8][C:9]2[NH:13][CH2:12][CH2:11][N:10]=2)=[C:3]([Cl:14])[CH:2]=1

Komponenten

4

Edukt 3

HCID 11177Magnesium StearateHCID 20179Clonidine HydrochlorideHCID 24441Calcium hydrogen phosphate

Produkt 1

HCID 2803Clonidine

Versuchsvorschrift

Basically 0.1 mg (base equivalent) of clonidine hydrochloride was blended with 13 mg of calcium phosphate dibasic, with 15 mg of microcrystalline cellulose, with 40 mg of hydroxypropyl methyl cellulose, 1 mg of colloidal silica and 0.9 mg of magnesium stearate.

Quellen und Nachweise

ORD-Eintrag
ord-3dcf1e25c5e44415a5fca05c8929c813
Quelldatensatz
uspto-grants-2015_11
Patentnummer
US09192599B2

Verknüpfte Notizen

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