Benzaldehyde → HCID 178418819, Verbindung

HRID 7510

Reaktionsgleichung

Reaktionsgleichung von HRID 7510
[NH2:1][C:2]1[S:3][CH:4]=[CH:5][N:6]=1.[C:7]([N+:11]#[C-:12])([CH3:10])([CH3:9])[CH3:8].[CH:13](=O)[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1.[C:21]([Cl:24])(=[O:23])[CH3:22]>Cl(O)(=O)(=O)=O>[Cl-:24].[C:21]([N+:1]1[C:13]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)=[C:12]([NH:11][C:7]([CH3:10])([CH3:9])[CH3:8])[N:6]2[CH:5]=[CH:4][S:3][C:2]=12)(=[O:23])[CH3:22]

Komponenten

6

Edukt 4

HCID 240BenzaldehydeHCID 21552-AminothiazoleHCID 6367Acetyl chlorideHCID 23577Tert-Butyl isocyanide

Produkt 1

HCID 178418819HCID 178418819, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 24247Perchloric AcidLösungsmittel

Versuchsvorschrift

Example 4 was carried out in accordance with the general directions for synthesis in process step a) from 1.0 ml (0.1 mmol) 2-amino-thiazole (0.1 M, DCM), 0.575 ml (0.115 mmol) tert.-butylisonitrile solution (0.2 M, DCM), 0.500 ml (0.15 mmol) benzaldehyde solution (0.3 M, DCM) and 10 μl perchloric acid (w=20%) and in process step c) and d) by reacting the resultant reaction product with 0.4 mmol acetylchloride.

Quellen und Nachweise

ORD-Eintrag
ord-3530e699346948b5a62efd1270abe4aa
Quelldatensatz
uspto-grants-2006_08
Patentnummer
US07087607B2

Verknüpfte Notizen

Wird geladen…