Alpha-Aminobutyric Acid → 2-(Acetylamino)butanoic acid

HRID 7535

Reaktionsgleichung

Reaktionsgleichung von HRID 7535
[NH2:1][CH:2]([CH2:6][CH3:7])[C:3]([OH:5])=[O:4].[C:8](OC(=O)C)(=[O:10])[CH3:9]>C(O)(=O)C>[C:8]([NH:1][CH:2]([CH2:6][CH3:7])[C:3]([OH:5])=[O:4])(=[O:10])[CH3:9]

Komponenten

4

Edukt 2

HCID 6657Alpha-Aminobutyric AcidHCID 7918Acetic Anhydride

Produkt 1

HCID 3061072-(Acetylamino)butanoic acid

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 176Acetic AcidLösungsmittel

Reaktionsbedingungen

Temperatur
100 °C

Versuchsvorschrift

163 g (1.58 mol) 2-aminobutanoic acid are dissolved in acetic acid, and 242 g (2.37 mol) acetic anhydride are added dropwise. The mixture is stirred for 2 h at 100° C. until completion of reaction, then the solution evaporated to dryness in vacuo. The solid residue is suspended in ethyl acetate, filtered and washed with diethyl ether.

Aufarbeitung

  1. customthe solution evaporated to dryness in vacuo
  2. filtrationfiltered
  3. washwashed with diethyl ether

Quellen und Nachweise

ORD-Eintrag
ord-4825907718a34102b76de664069c39ba
Quelldatensatz
uspto-grants-2006_08
Patentnummer
US07087605B2

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