Water → N-(7-Oxo-4,5,6,7-tetrahydro-1-benzothiophen-4-yl)formamide

HRID 839745Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 839745
S1CCS[C:2]21[C:10]1[S:11][CH:12]=[CH:13][C:9]=1[CH:8]([NH:14][CH:15]=[O:16])[CH2:7][CH2:6]2.O.C(=O)([O-])[O-:19].[Ca+2]>C(#N)C>[O:19]=[C:2]1[C:10]2[S:11][CH:12]=[CH:13][C:9]=2[CH:8]([NH:14][CH:15]=[O:16])[CH2:7][CH2:6]1

Komponenten

5

Edukt 3

HCID 962WaterHCID 10112Calcium CarbonateHCID 86735494N-(5,6-dihydrospiro[benzo-[b]thiophen-7(4H), 2'-[1,3]dithiolan]-4-yl)formamide

Produkt 1

HCID 23347790N-(7-Oxo-4,5,6,7-tetrahydro-1-benzothiophen-4-yl)formamide

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6342AcetonitrileLösungsmittel2×

Versuchsvorschrift

To a stirred mixture of N-(5,6-dihydrospiro[benzo-[b]thiophen-7(4H), 2'-[1,3]dithiolan]-4-yl)formamide (1.5 g), acetonitrile (20 ml) and water is added calcium carbonate (1.65 g) and mercuric chloride (3.0 g). The mixture is stirred at room temperature for 35 minutes and acetonitrile is added. The solid is filtered and washed with acetonitrile. The filtrate (100 ml) is evaporated to dryness to afford the title compound.

Aufarbeitung

  1. filtrationThe solid is filtered
  2. washwashed with acetonitrile
  3. customThe filtrate (100 ml) is evaporated to dryness

Quellen und Nachweise

ORD-Eintrag
ord-713ce4782ce747b09cbf1e4a9bc7fe22
Quelldatensatz
uspto-grants-1978_06
Patentnummer
US04096155

Notizen zur Reaktion

Wird geladen…