Hydrochloric Acid → 3-(2,6-Dichlorobenzoyl)-1-(p-chlorophenyl)-hydantoin

HRID 847467

Reaktionsgleichung

Reaktionsgleichung von HRID 847467
[Cl:1][C:2]1[CH:20]=[CH:19][CH:18]=[C:17]([Cl:21])[C:3]=1[C:4]([NH:6][C:7]([NH:9][C:10]1[CH:15]=[CH:14][C:13]([Cl:16])=[CH:12][CH:11]=1)=[O:8])=[O:5].[C:22](Cl)(=O)[C:23](Cl)=[O:24].NC(N)=O.Cl>ClCCCl>[Cl:1][C:2]1[CH:20]=[CH:19][CH:18]=[C:17]([Cl:21])[C:3]=1[C:4]([N:6]1[C:23](=[O:24])[CH2:22][N:9]([C:10]2[CH:11]=[CH:12][C:13]([Cl:16])=[CH:14][CH:15]=2)[C:7]1=[O:8])=[O:5]

Komponenten

6

Edukt 4

HCID 313Hydrochloric AcidHCID 1176UreaHCID 65578Oxalyl chlorideHCID 923002,6-dichloro-N-(((4-chlorophenyl)amino)carbonyl)benzamide

Produkt 1

HCID 190064153-(2,6-Dichlorobenzoyl)-1-(p-chlorophenyl)-hydantoin

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 111,2-DichloroethaneLösungsmittel

Versuchsvorschrift

10.3 g of N-(2,6-dichlorobenzoyl)-N'-(p-chlorophenyl)-urea are boiled in 100 ml of dry 1,2-dichloroethane containing 3 ml of oxalylchloride for 24 hours. The urea dissolves with the evolution of hydrochloric acid. After concentration by evaporation and after the addition of 25 ml of ligroin the residue becomes crystalline. The substance mauy be recrystallized from 30 mls of benzene. Melting point 157° C. Yield 8 g.

Aufarbeitung

  1. concentrationAfter concentration
  2. customby evaporation
  3. additionafter the addition of 25 ml of ligroin the residue
  4. customThe substance mauy be recrystallized from 30 mls of benzene

Quellen und Nachweise

ORD-Eintrag
ord-1d4e2ea2bb504f7b8f8c05fc2fff3709
Quelldatensatz
uspto-grants-1992_08
Patentnummer
US05142064

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