Bromine → 5-Bromo-3,3-dimethylbenzofuran-2(3H)-one

HRID 858591

Reaktionsgleichung

Reaktionsgleichung von HRID 858591
[CH3:1][C:2]1([CH3:12])[C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[O:4][C:3]1=[O:11].[Br:13]Br>C(O)(=O)C>[Br:13][C:8]1[CH:9]=[CH:10][C:5]2[O:4][C:3](=[O:11])[C:2]([CH3:12])([CH3:1])[C:6]=2[CH:7]=1

Komponenten

4

Edukt 2

HCID 24408BromineHCID 5956202(3H)-Benzofuranone, 3,3-dimethyl-

Produkt 1

HCID 162206345-Bromo-3,3-dimethylbenzofuran-2(3H)-one

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 176Acetic AcidLösungsmittel

Versuchsvorschrift

3,3-Dimethyl-3H-benzofuran-2-one (2.81 g, 17.3 mmol) was added to a solution of Bromine (1.51 mL, 29.5 mmoL) and Acetic acid (35 mL) at room temperature, then stirred overnight. The resulting mixture was stripped of solvent, then distilled under high vacuum. The product fraction (2.08 g, 50%) was collected between 65° C. and 79° C.

Aufarbeitung

  1. distillationdistilled under high vacuum
  2. customThe product fraction (2.08 g, 50%) was collected between 65° C. and 79° C.

Quellen und Nachweise

ORD-Eintrag
ord-d713a1dfac634009a7cc69c2a7c1e159
Quelldatensatz
uspto-grants-2006_12
Patentnummer
US07148226B2

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