Sodium Hydroxide → Leucinamide

HRID 864277

Reaktionsgleichung

Reaktionsgleichung von HRID 864277
[NH2:1][C@H:2]([C:7]([NH2:9])=[O:8])[CH2:3][CH:4]([CH3:6])[CH3:5].Cl.[OH-].[Na+]>CC(N(C)C)=O.O>[NH2:1][C@H:2]([C:7]([NH2:9])=[O:8])[CH2:3][CH:4]([CH3:6])[CH3:5]

Komponenten

5

Edukt 2

HCID 14798Sodium HydroxideHCID 2733199Leucinamide hydrochloride

Produkt 1

HCID 69640Leucinamide

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 962WaterLösungsmittelHCID 31374DimethylacetamideLösungsmittel2×

Versuchsvorschrift

1.25M solution of Leu-NH2 in DMAC was prepared by dissolving Leu-NH2.HCl (1.33 g, 7.98 mmol) in 5.0 mL of water, titrating to pH 8.0 with 1M NaOH, lyophilizing, and taking up the residue in 6.4 ml of DMAC. The NaCl precipitate was removed by filtering through a fine glass frit to give a clear solution of pH 9.25.

Aufarbeitung

  1. customThe NaCl precipitate was removed
  2. filtrationby filtering through a fine glass frit
  3. customto give a clear solution of pH 9.25

Quellen und Nachweise

ORD-Eintrag
ord-b5d127ef1e6044608b68a102b37d5fbf
Quelldatensatz
uspto-grants-1996_10
Patentnummer
US05563044

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